Impairment of Cerebral Blood Flow Autoregulation in the Newborn Lamb by Hypoxia
نویسندگان
چکیده
منابع مشابه
Autoregulation of Cerebral Blood Flow
Autoregulation of cerebral blood flow (constant perfusion despite variations in blood pressure) was studied in 15 control subjects and in 24 patients with cerebral vascular lesions. Thirteen patients were studied within the first 2 days of an episode of cerebral ischemia ("acute" group); 11 were studied from 15 days to several months after an ischemic episode ("chronic" group). Measurements of ...
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Cerebral blood flow autoregulation (CBFA) to changes in perfusion pressure has not been previously reported in the rat. A modification of the Kety and Schmidt technique employing 133Xenon was used to measure cerebral blood flow (CBF) in paralyzed adult Sprague Dawley rats passively ventilated with 70% nitrous oxide and 30% oxygen. At a mean arterial blood pressure (MABP) of 121 +/- 19 mm Hg, an...
متن کاملObservations on the control of cerebral blood flow in the sheep fetus and newborn lamb.
Cerebral blood flow was measured with xenon in 21 fetal sheep and 14 newborn lambs under 48 hours old. When the ewe breathed air, the average gray matter blood flow in the fetuses was 70.6 ml/100 g/min, the average white matter blood flow 15.4 ml/100 g/min and average gray matter oxygen consumption 2.06 ml/100 g/min. The corresponding values in the newborn lambs were 87.2, 17.8, and 2.98 ml/100...
متن کاملModelling cerebral blood flow autoregulation in humans
Better understanding of the determinants of cerebral blood flow (CBF) and the interpretation of clinical measurements can benefit from quantitative modelling of CBF regulatory mechanisms and their interaction with other haemodynamic variables such as intracranial pressure and blood gases. Mathematical models have been able to reproduce many known phenomena and to extract relevant parameters for...
متن کاملAlterations in cerebral autoregulation and cerebral blood flow velocity during acute hypoxia: rest and exercise.
We examined the relationship between changes in cardiorespiratory and cerebrovascular function in 14 healthy volunteers with and without hypoxia [arterial O(2) saturation (Sa(O(2))) approximately 80%] at rest and during 60-70% maximal oxygen uptake steady-state cycling exercise. During all procedures, ventilation, end-tidal gases, heart rate (HR), arterial blood pressure (BP; Finometer) cardiac...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1986
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198606000-00007